The cases reported in BMJ involved excesses, says Chris Perille, a spokesman for the William Wrigley Jr. Company, which makes chewing gum containing sorbitol (including its brands Extra, Orbit, Freedent, and Eclipse).
"To reach the threshold of excessive consumption of sorbitol through use of gum alone [at levels set by the FDA], someone would have to chew close to 50 sticks or 100 pellets of gum daily," he says. In the U.S., he adds, the average per capita gum consumption is just one stick every other day.
The ingredient is safe and effective "when used as directed," adds Tonia Elrod, a spokeswoman for Procter & Gamble, the manufacturer of Crest toothpaste, which contains sorbitol.
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